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Index > Protein center > CYP11A1(Gene name) > Bovine
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  • CYP11A1 (Gene name),
  • Cholesterol side-chain cleavage enzyme, mitochondrial (Protein name ),  CP11A_BOVIN from NCBI database.
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  • General Annotation
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  • Gene name:
    CYP11A1;
    Protein name:
    Cholesterol side-chain cleavage enzyme, mitochondrial;
    Alternative:
    Cholesterol desmolase;CYPXIA1;Cytochrome P450(scc);Cytochrome P450 11A1;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone.
    Subcellular Location:
    Mitochondrion membrane
    Protein Attributes:
    Sequence length:
    520
    Sequence:
    50:
    MLARGLPLRS | ALVKACPPIL | STVGEGWGHH | RVGTGEGAGI | STKTPRPYSE | 
    100:
    IPSPGDNGWL | NLYHFWREKG | SQRIHFRHIE | NFQKYGPIYR | EKLGNLESVY | 
    150:
    IIHPEDVAHL | FKFEGSYPER | YDIPPWLAYH | RYYQKPIGVL | FKKSGTWKKD | 
    200:
    RVVLNTEVMA | PEAIKNFIPL | LNPVSQDFVS | LLHKRIKQQG | SGKFVGDIKE | 
    250:
    DLFHFAFESI | TNVMFGERLG | MLEETVNPEA | QKFIDAVYKM | FHTSVPLLNV | 
    300:
    PPELYRLFRT | KTWRDHVAAW | DTIFNKAEKY | TEIFYQDLRR | KTEFRNYPGI | 
    350:
    LYCLLKSEKM | LLEDVKANIT | EMLAGGVNTT | SMTLQWHLYE | MARSLNVQEM | 
    400:
    LREEVLNARR | QAEGDISKML | QMVPLLKASI | KETLRLHPIS | VTLQRYPESD | 
    450:
    LVLQDYLIPA | KTLVQVAIYA | MGRDPAFFSS | PDKFDPTRWL | SKDKDLIHFR | 
    500:
    NLGFGWGVRQ | CVGRRIAELE | MTLFLIHILE | NFKVEMQHIG | DVDTIFNLIL | 
    520:
    TPDKPIFLVF | RPFNQDPPQA | 
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
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    E0987b
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    ELISA Kit for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Cat.:
    E0987m
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    Packing:
    96T
    ELISA Kit for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Cat.:
    E0987h
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    ELISA Kit for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Cat.:
    E0987p
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    Packing:
    96T
    ELISA Kit for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Cat.:
    E0987r
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    Packing:
    96T
    ELISA Kit for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    MSDS:
    Please sign in first.
    CLIA Kit for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Cat.:
    U0987r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Cat.:
    U0987m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Cat.:
    U0987h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    MSDS:
    Please sign in first.
    CLIA Kit for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Cat.:
    U0987p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Cat.:
    U0987b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Polyclonal Antibody for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Polyclonal Antibody for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Cat.:
    P0987Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Cat.:
    P0987Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Polyclonal Antibody for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Cat.:
    P0987Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Monoclonal Antibody for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Monoclonal Antibody for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Monoclonal Antibody for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Monoclonal Antibody for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Monoclonal Antibody for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Protein for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Protein for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Protein for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Protein for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Protein for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial
    Protein for Bovine Cholesterol side-chain cleavage enzyme, mitochondrial

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    References
    1. 1.
      "Molecular cloning and nucleotide sequence of cDNA for mRNA of mitochondrial cytochrome P-450(SCC) of bovine adrenal cortex."
      Morohashi K. , Fujii-Kuriyama Y. , Okada Y. , Sogawa K. , Hirose T. , Inayama S. , Omura T.
      Proc. Natl. Acad. Sci. U.S.A.81:4647-4651(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Adrenal cortex.
    2. 2.
      "Primary structure of the cholesterol side-chain cleavage cytochrome P-450 from bovine adrenocortical mitochondria and some aspects of its functioning on a structural level."
      Chashchin V.L. , Lapko V.N. , Adamovich T.B. , Lapko A.G. , Kuprina N.S. , Akhrem A.A.
      Biochim. Biophys. Acta871:217-223(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 40-520
    3. 3.
      "Partial amino acid sequences of two mitochondrial and two microsomal cytochrome P-450's from adrenal cortex."
      Ogishima T. , Okada Y. , Kominami S. , Takemori S. , Omura T.
      J. Biochem.94:1711-1714(1983) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 40-54
    4. 4.
      "Characterization of the promoter/regulatory region of the bovine CYP11A (P-450scc) gene. Basal and cAMP-dependent expression."
      Ahlgren R. , Simpson E.R. , Waterman M.R. , Lund J.
      J. Biol. Chem.265:3313-3319(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-90
    5. 5.
      "Molecular modeling of the 3-D structure of cytochrome P-450scc."
      Vijayakumar S. , Salerno J.C.
      Biochim. Biophys. Acta1160:281-286(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: 3D-STRUCTURE MODELING OF 40-520
    6. 6.
      "Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme CYP11A1."
      Mast N. , Annalora A.J. , Lodowski D.T. , Palczewski K. , Stout C.D. , Pikuleva I.A.
      J. Biol. Chem.286:5607-5613(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 41-520 IN COMPLEX WITH HEME AND 22R-HYDROXYCHOLESTEROL;COFACTOR
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